Description

Imrecoxib is a highly selective cyclooxygenase-2 (COX-2) inhibitor, representing a significant class of non-steroidal anti-inflammatory drugs (NSAIDs). Its primary value lies in providing potent anti-inflammatory and analgesic effects with a potentially improved gastrointestinal safety profile compared to traditional NSAIDs. This makes it a critical active pharmaceutical ingredient (API) for researchers and manufacturers developing next-generation pain management and anti-inflammatory therapeutics. The compound is essential for pharmaceutical R&D, formulation development, and the production of finished dosage forms targeting conditions like osteoarthritis and rheumatoid arthritis.

Application

• Primary Active Pharmaceutical Ingredient (API) in prescription anti-inflammatory and analgesic medications.
• Key intermediate in advanced pharmaceutical research and development for novel COX-2 inhibitors.
• Reference standard for analytical method development and quality control in pharmaceutical laboratories.
• Biochemical research tool for studying COX-2 enzyme pathways and inflammation mechanisms.
• Formulation development for solid oral dosage forms such as tablets and capsules.
• Preclinical and clinical studies evaluating efficacy and safety profiles of new therapeutic agents.

Basic Information

Product Name	Imrecoxib
CAS No.	896729-07-0
Molecular Formula	C16H14N2O3S
Molecular Weight	314.36 g/mol
Synonyms	4-(4-Methylsulfonylphenyl)-3-phenyl-5H-furan-2-one; BAP-909; Imrecoxibum; UNII-7V515P4U3W; COX-2 Inhibitor BAP-909; 3-Phenyl-4-(4-(methylsulfonyl)phenyl)-2(5H)-furanone
EINECS	Contact for details

Quality Control

Our Imrecoxib is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting high-grade pharmaceutical standards. Certificates of Analysis (COA) detailing specifications such as assay, related substances, residual solvents, and heavy metals are provided with every shipment. We support compliance with cGMP, ICH Q7, and other relevant pharmacopeial guidelines for active pharmaceutical ingredients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 0.5%
Sulfated Ash	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.