Description

(4-Isobutyl-Piperazin-1-Yl)-Acetic Acid Dihydrochloride is a high-purity, pharmaceutically relevant piperazine derivative supplied as a stable dihydrochloride salt. This compound serves as a critical building block and intermediate in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research. It is essential for organizations in the pharmaceutical, biotechnology, and fine chemical sectors developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the research and development of new drug candidates, especially in central nervous system (CNS) and cardiovascular therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries via structure-activity relationship (SAR) studies.
• API Synthesis: Integral building block in the multi-step synthesis of complex target molecules for preclinical and clinical trials.
• Bioconjugation & Probe Development: The acetic acid moiety and piperazine nitrogen allow for functionalization, useful in creating diagnostic probes or targeted drug conjugates.
• Chemical Biology: Employed in the study of biological pathways and target identification due to its modifiable pharmacophore.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for GMP and non-GMP scale-up projects.

Basic Information

Product Name	(4-Isobutyl-Piperazin-1-Yl)-Acetic Acid Dihydrochloride
CAS No.	896523-61-8
Molecular Formula	C10H21Cl2N2O2
Molecular Weight	281.19 g/mol
Synonyms	2-(4-Isobutylpiperazin-1-yl)acetic acid dihydrochloride; 1-Isobutyl-4-(carboxymethyl)piperazine dihydrochloride; Acetic acid, 2-(4-isobutyl-1-piperazinyl)-, dihydrochloride; (4-Isobutyl-1-piperazinyl)acetic acid dihydrochloride; 896523-61-8; UNII-8K4F8G8Q4S; 8K4F8G8Q4S
EINECS	Contact for details

Quality Control

Our (4-Isobutyl-Piperazin-1-Yl)-Acetic Acid Dihydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing identity, purity, and impurity profiles. Our quality system supports compliance with ISO standards, and we can supply material tailored to specific project requirements, including those for early-phase pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.