Description

3-(4-Acetylpiperazin-1-Yl)Benzoic Acid is a high-purity pharmaceutical intermediate and building block featuring a benzoic acid core linked to an acetylpiperazine moiety. This compound is valued for its role as a versatile synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and fine chemical sectors seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to optimize lead compounds.
• API Development: Serves as a precursor in the multi-step synthesis of complex active pharmaceutical ingredients.
• Bioconjugation & Probe Synthesis: The carboxylic acid group allows for coupling reactions to create labeled compounds for biochemical assays.
• Agrochemical Research: Employed in the development of new herbicides or fungicides with novel modes of action.
• Academic & Institutional R&D: Used in university and research institute laboratories for exploratory synthetic projects.

Basic Information

Product Name	3-(4-Acetylpiperazin-1-Yl)Benzoic Acid
CAS No.	896516-75-9
Molecular Formula	C13H16N2O3
Molecular Weight	248.28 g/mol
Synonyms	3-(4-Acetyl-1-piperazinyl)benzoic acid; 1-[3-(Carboxyphenyl)]-4-acetylpiperazine; Benzoic acid, 3-(4-acetyl-1-piperazinyl)-; 3-(4-Acetylpiperazin-1-yl)benzoic acid; 896516-75-9; 3-(N-Acetylpiperazino)benzoic acid; 4-Acetyl-1-(3-carboxyphenyl)piperazine
EINECS	Contact for details

Quality Control

Our 3-(4-Acetylpiperazin-1-Yl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.