Description

tert-Butyl 2,7-diazaspiro[3.5]nonane-7-carboxylate is a high-value, nitrogen-containing spirocyclic building block essential for modern pharmaceutical and agrochemical research. Its unique rigid, three-dimensional scaffold is prized for modulating the physicochemical properties and biological activity of novel compounds. This intermediate is primarily utilized by medicinal chemists and process development scientists in the synthesis of new chemical entities, particularly for central nervous system (CNS) and anti-infective targets.

Application

• Pharmaceutical Intermediate: A key scaffold in the research and development of novel drug candidates, especially for neurological disorders and psychiatric conditions.
• Medicinal Chemistry: Used to introduce conformational constraint and improve metabolic stability, solubility, and selectivity in lead optimization programs.
• Agrochemical Synthesis: Serves as a precursor in the development of new pesticides and herbicides with novel modes of action.
• Chemical Biology: Employed as a versatile building block for creating molecular probes and tool compounds to study biological pathways.
• Process Chemistry: Used in the scale-up and route development for the commercial manufacturing of active pharmaceutical ingredients (APIs).
• Library Synthesis: A valuable reactant for generating diverse compound libraries in high-throughput screening campaigns.

Basic Information

Product Name	tert-Butyl 2,7-diazaspiro[3.5]nonane-7-carboxylate
CAS No.	896464-16-7
Molecular Formula	C12H22N2O2
Molecular Weight	226.32 g/mol
Synonyms	7-Boc-2,7-diazaspiro[3.5]nonane; tert-Butyl 2,7-diazaspiro[3.5]nonane-7-carboxylate; 2,7-Diazaspiro[3.5]nonane-7-carboxylic acid, 1,1-dimethylethyl ester; 7-(tert-Butoxycarbonyl)-2,7-diazaspiro[3.5]nonane; Boc-2,7-diazaspiro[3.5]nonane; 2,7-Diazaspiro[3.5]nonane, N-Boc-protected; 1,1-Dimethylethyl 2,7-diazaspiro[3.5]nonane-7-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2,7-diazaspiro[3.5]nonane-7-carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with full analytical data are provided to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.