Description

Methyl 4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)benzoate CAS NO 896160-80-8 is a high-purity, advanced pharmaceutical intermediate characterized by its piperazine and trifluoromethyl functional groups. This compound is of significant commercial value for its role in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, including kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new drug candidates, especially those targeting protein kinases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to enhance drug potency and selectivity.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in multi-step synthetic routes for complex active molecules.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard for analytical method development and validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development pipelines.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacology projects.

Basic Information

Product Name	Methyl 4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)benzoate
CAS No.	896160-80-8
Molecular Formula	C15H19F3N2O2
Molecular Weight	316.32 g/mol
Synonyms	Methyl 4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)benzoate; Benzoic acid, 4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)-, methyl ester; 4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)benzoic acid methyl ester; Methyl 4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)benzoate; 896160-80-8; CAS-896160-80-8
EINECS	Contact for details

Quality Control

Our Methyl 4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; therefore, containers should be kept tightly sealed when not in use to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.