Description

2-Methoxy-4-((4-Methylpiperazin-1-yl)methyl)benzenamine is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular scaffold combining an aniline derivative with a methylpiperazine moiety. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially for central nervous system (CNS) and oncological targets.
• Chemical Research & Development: Serves as a versatile precursor for medicinal chemistry, enabling the exploration of structure-activity relationships (SAR).
• Active Pharmaceutical Ingredient (API) Synthesis: Used in multi-step synthetic routes to construct complex molecular architectures for final API production.
• Bioconjugation & Probe Development: The aniline and piperazine functional groups allow for derivatization, making it useful for creating biochemical probes and labeled compounds.

Basic Information

Product Name	2-Methoxy-4-((4-Methylpiperazin-1-yl)methyl)benzenamine
CAS No.	896128-19-1
Molecular Formula	C13H21N3O
Molecular Weight	235.33 g/mol
Synonyms	4-((4-Methylpiperazin-1-yl)methyl)-2-methoxybenzenamine; 2-Methoxy-4-[(4-methyl-1-piperazinyl)methyl]aniline; 2-Methoxy-4-(4-methylpiperazin-1-ylmethyl)aniline; Benzenamine, 2-methoxy-4-((4-methyl-1-piperazinyl)methyl)-; 896128-19-1; 4-(4-Methylpiperazin-1-ylmethyl)-2-methoxyaniline
EINECS	Contact for details

Quality Control

Our 2-Methoxy-4-((4-Methylpiperazin-1-yl)methyl)benzenamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.