Description

1-(3-Bromobenzyl)Piperidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 896046-55-2. This compound is a critical building block in modern medicinal chemistry, valued for its unique piperidine-carboxylic acid scaffold functionalized with a bromobenzyl group. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and development of new therapeutic agents, particularly for central nervous system (CNS) targets and other small molecule drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the multi-step synthesis of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Ligand and Probe Synthesis: Employed in the development of chemical probes and ligands for biological target validation and assay development.
• Chemical Biology: Utilized in the synthesis of tool compounds for studying enzyme function and receptor interactions.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for clients.

Basic Information

Product Name	1-(3-Bromobenzyl)Piperidine-3-Carboxylic Acid
CAS No.	896046-55-2
Molecular Formula	C14H18BrNO2
Molecular Weight	312.20 g/mol
Synonyms	3-[(3-Bromophenyl)methyl]piperidine-3-carboxylic acid; 1-[(3-Bromophenyl)methyl]-3-piperidinecarboxylic acid; 1-(3-Bromobenzyl)nipecotic acid; 896046-55-2; 3-Carboxy-1-(3-bromobenzyl)piperidine; 1-(3-Bromobenzyl)-3-piperidinecarboxylic Acid; 3-Piperidinecarboxylic acid, 1-[(3-bromophenyl)methyl]-
EINECS	Contact for details

Quality Control

Our 1-(3-Bromobenzyl)Piperidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment to ensure it meets the stringent requirements of research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.