Description

2H-Pyrido[1,2-A]Pyrazine-1,8-Dione, 6-Bromo-2-[(4-Fluorophenyl)Methyl]-3,4-Dihydro-9-Hydroxy- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research targeting central nervous system and oncological therapies. It is essential for medicinal chemistry research, process development, and scale-up manufacturing within the pharmaceutical and biotechnology industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates and novel chemical entities.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies for new therapeutic targets.
• Process Chemistry & Scale-Up: Serves as a defined starting material or intermediate in the development and optimization of commercial-scale API manufacturing routes.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical sector.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.

Basic Information

Product Name	2H-Pyrido[1,2-A]Pyrazine-1,8-Dione, 6-Bromo-2-[(4-Fluorophenyl)Methyl]-3,4-Dihydro-9-Hydroxy-
CAS No.	895133-42-3
Molecular Formula	C15H12BrFN2O3
Molecular Weight	367.17 g/mol
Synonyms	6-Bromo-2-[(4-fluorophenyl)methyl]-9-hydroxy-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,8-dione; 9-Hydroxy-6-bromo-2-(4-fluorobenzyl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,8-dione; 6-Bromo-2-(4-fluorobenzyl)-9-hydroxy-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,8-dione; CAS 895133-42-3; Bromo-fluorophenylmethyl dihydroxypyridopyrazinedione
EINECS	Contact for details

Quality Control

Our 2H-Pyrido[1,2-A]Pyrazine-1,8-Dione, 6-Bromo-2-[(4-Fluorophenyl)Methyl]-3,4-Dihydro-9-Hydroxy- is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.