Description

2-Chloro-6-(3-Fluorophenoxy) Pyrazine is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 894416-95-6. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic chemistry. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug molecules, especially kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging its pyrazine core for biological activity.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Material Science: Potential precursor for the synthesis of specialty chemicals and functional materials, such as ligands for catalysis.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	2-Chloro-6-(3-Fluorophenoxy) Pyrazine
CAS No.	894416-95-6
Molecular Formula	C10H6ClFN2O
Molecular Weight	224.62 g/mol
Synonyms	2-Chloro-6-(3-fluorophenoxy)pyrazine; 6-Chloro-3-(3-fluorophenoxy)pyrazine; Pyrazine, 2-chloro-6-(3-fluorophenoxy)-; 894416-95-6; 3-Fluorophenoxy pyrazine derivative; 2-Chloro-6-(m-fluorophenoxy)pyrazine
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-6-(3-Fluorophenoxy) Pyrazine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for pharmaceutical R&D and scale-up. A detailed Certificate of Analysis (COA) including HPLC purity, identity confirmation (IR, NMR), and impurity profile is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.