Description

1-(2-Fluorobenzyl)Piperazin-2-One is a high-purity fluorinated piperazinone derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in providing a versatile scaffold for constructing complex molecules with tailored biological and physical properties. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets and kinase inhibitors.
• Agrochemical Research: Used in developing new active ingredients for crop protection products, leveraging the fluorine atom for enhanced metabolic stability and bioavailability.
• Chemical Biology Probe Synthesis: Serves as a core structure for creating molecular probes to study enzyme function and biological pathways.
• Material Science Applications: Investigated as a monomer or additive for specialty polymers, where the fluorobenzyl group can impart specific solubility or surface properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific synthesis projects.

Basic Information

Product Name	1-(2-Fluorobenzyl)Piperazin-2-One
CAS No.	893747-85-8
Molecular Formula	C11H13FN2O
Molecular Weight	208.23 g/mol
Synonyms	1-[(2-Fluorophenyl)methyl]-2-piperazinone; 2-Fluorobenzylpiperazinone; 1-(2-Fluorobenzyl)-2-piperazinone; 1-(2-Fluorobenzyl)piperazin-2-one; 893747-85-8; 2-Piperazinone, 1-[(2-fluorophenyl)methyl]-; Fluorobenzyl piperazinone derivative
EINECS	Contact for details

Quality Control

Our 1-(2-Fluorobenzyl)Piperazin-2-One is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.