Description

Pyrido[2,3-B]Pyrazine-8-Carboxylic Acid is a high-purity heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. This compound is valued for its unique fused bicyclic structure, which serves as a critical scaffold in the development of novel pharmacologically active molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting kinase inhibition and other therapeutic pathways.
• Medicinal Chemistry Research: Used as a versatile building block for constructing novel heterocyclic libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Employed in the research and synthesis of new active ingredients for crop protection products.
• Material Science: Serves as an organic precursor for the development of specialty chemicals and functional materials, including ligands for catalysis.
• Contract Research & Manufacturing (CRAM): Supplied to organizations engaged in custom synthesis and process development for client projects.

Basic Information

Product Name	Pyrido[2,3-B]Pyrazine-8-Carboxylic Acid
CAS No.	893723-38-1
Molecular Formula	C8H5N3O2
Molecular Weight	175.15 g/mol
Synonyms	8-Pyrido[2,3-b]pyrazinecarboxylic acid; Pyrido[2,3-b]pyrazine-8-carboxylic acid; 1,6-Naphthyridine-8-carboxylic acid; 8-Carboxypyrido[2,3-b]pyrazine; 1,6-Naphthyridine-3-carboxylic acid (related isomer); A-83-01 (common research compound precursor); ALK5 Inhibitor II precursor; TGF-β receptor inhibitor intermediate.
EINECS	Contact for details

Quality Control

Our Pyrido[2,3-B]Pyrazine-8-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.