Description

5-Bromo-3-(2-Pyridin-3-Yl-Pyrrolidin-1-Yl)-Pyrazin-2-Ylamine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the research and development of novel therapeutic agents, particularly in kinase inhibitor programs. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules. The precise molecular architecture of this intermediate enables the exploration of new chemical entities in drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of targeted small-molecule drugs, especially kinase inhibitors.
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Biochemical Tool Compound Development: Employed in the development of chemical probes for studying specific biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	5-Bromo-3-(2-Pyridin-3-Yl-Pyrrolidin-1-Yl)-Pyrazin-2-Ylamine
CAS No.	893612-17-4
Molecular Formula	C13H14BrN5
Molecular Weight	328.19 g/mol
Synonyms	5-Bromo-3-[2-(3-pyridinyl)-1-pyrrolidinyl]-2-pyrazinamine; 2-Pyrazinamine, 5-bromo-3-[2-(3-pyridinyl)-1-pyrrolidinyl]-; 5-Bromo-3-(2-(pyridin-3-yl)pyrrolidin-1-yl)pyrazin-2-amine; 893612-17-4; CAS-893612-17-4
EINECS	Contact for details

Quality Control

Our production of 5-Bromo-3-(2-Pyridin-3-Yl-Pyrrolidin-1-Yl)-Pyrazin-2-Ylamine adheres to stringent quality management protocols. Each batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality systems are designed to support cGMP compliance for pharmaceutical applications, ensuring traceability and documentation meet industry expectations.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maximize stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.