Description

2-Amino-5-Bromo-3-Pyrrolidin-1-Ylpyrazine is a high-purity, advanced pharmaceutical intermediate with a distinct pyrazine core structure. This compound matters for its critical role as a versatile building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) research. Pharmaceutical R&D teams and fine chemical manufacturers need this specialized intermediate to develop next-generation therapeutic agents and novel molecular entities.

Application

• Key synthetic intermediate in the development of kinase inhibitor drug candidates for oncology applications.
• Building block for the research and synthesis of CNS-targeting compounds, including potential antipsychotics and antidepressants.
• Precursor in the manufacture of specialty agrochemicals, such as novel fungicides and herbicides.
• Versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Starting material for the production of custom ligands and catalysts used in asymmetric synthesis.
• Critical component in the synthesis of fluorescent dyes and molecular probes for biochemical research and diagnostics.

Basic Information

Product Name	2-Amino-5-Bromo-3-Pyrrolidin-1-Ylpyrazine
CAS No.	893611-72-8
Molecular Formula	C8H12BrN5
Molecular Weight	258.12 g/mol
Synonyms	5-Bromo-2-amino-3-(1-pyrrolidinyl)pyrazine; 3-(Pyrrolidin-1-yl)-5-bromopyrazin-2-amine; 5-Bromo-3-(pyrrolidin-1-yl)pyrazin-2-amine; 2-Amino-5-bromo-3-(1-pyrrolidinyl)pyrazine; 893611-72-8; 5-Bromo-2-amino-3-pyrrolidin-1-ylpyrazine; Pyrrolidin-1-yl-pyrazine derivative; Bromoaminopyrazine pyrrolidine derivative
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Bromo-3-Pyrrolidin-1-Ylpyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to support your regulatory and R&D documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.