Description

[1-(6-Methylpyrazin-2-Yl)Piperid-4-Yl]Methylamine is a high-purity, advanced pharmaceutical intermediate featuring a piperidine-pyrazine hybrid scaffold. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules targeting central nervous system and metabolic disorders. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, especially those targeting GPCRs and kinase enzymes.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its privileged heterocyclic structure.
• Biochemical Tool Compound: Acts as a precursor for developing labeled probes or inhibitors for pharmacological and biological assays.
• Contract Manufacturing: Supplied to CDMOs for scale-up synthesis under cGMP conditions for clinical trial material production.
• Academic Research: Employed in university and institutional labs for exploratory synthetic chemistry and drug discovery projects.

Basic Information

Item	Details
Product Name	[1-(6-Methylpyrazin-2-Yl)Piperid-4-Yl]Methylamine
CAS No.	892502-20-4
Molecular Formula	C11H18N4
Molecular Weight	206.29 g/mol
Synonyms	1-(6-Methylpyrazin-2-yl)piperidin-4-ylmethanamine; 4-(Aminomethyl)-1-(6-methyl-2-pyrazinyl)piperidine; 1-(6-Methyl-2-pyrazinyl)-4-piperidinemethanamine; (1-(6-Methylpyrazin-2-yl)piperidin-4-yl)methanamine; UNII-9J1V6Q6D0I; 9J1V6Q6D0I; 892502-20-4; 1-(6-Methylpyrazin-2-yl)piperidine-4-methylamine
EINECS	Contact for details

Quality Control

Our [1-(6-Methylpyrazin-2-Yl)Piperid-4-Yl]Methylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and rigorous control of residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications and test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged operations to ensure stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.