Description

O,O'-Bis(2-Aminoethyl)Octadecaethylene Glycol is a high-purity, multi-functional polyethylene glycol (PEG) derivative featuring primary amine termini. This compound is engineered to serve as a versatile linker and hydrophilic spacer in advanced material synthesis and bioconjugation. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and specialty polymer industries who require precise, reproducible, and high-quality building blocks for creating functionalized surfaces, drug delivery systems, and hydrogels.

Application

• Bioconjugation and Drug Delivery: Acts as a hydrophilic PEG spacer to link therapeutic agents (e.g., proteins, peptides, small molecule drugs) to carriers, antibodies, or targeting ligands, enhancing solubility and circulation time.
• Surface Functionalization: Used to create amine-terminated self-assembled monolayers (SAMs) on gold, silicon, or polymer surfaces for subsequent immobilization of biomolecules in biosensor and diagnostic device fabrication.
• Crosslinking Agent for Hydrogels: Serves as a water-soluble crosslinker in the synthesis of PEG-based hydrogels for tissue engineering scaffolds, wound dressings, and controlled-release matrices.
• Polymer Modification: Employed as a macromonomer or chain extender to introduce reactive amine groups into polymer backbones, enabling further functionalization in specialty polymer synthesis.
• Nanoparticle Capping and Stabilization: Utilized to functionalize and stabilize metallic or polymeric nanoparticles, providing a biocompatible coating and a handle for attaching targeting moieties.
• Intermediate for Specialty Surfactants: Functions as a key intermediate in the production of non-ionic, amine-functional surfactants and emulsifiers for specialized formulations.

Basic Information

Product Name	O,O'-Bis(2-Aminoethyl)Octadecaethylene Glycol
CAS No.	892154-56-2
Molecular Formula	C42H86N2O20
Molecular Weight	963.13 g/mol
Synonyms	α,ω-Bis(2-aminoethoxy)poly(oxy-1,2-ethanediyl); PEG900 Diamine; Poly(ethylene glycol) bis(2-aminoethyl) ether (Mn ~900); 2,2'-(Ethane-1,2-diylbis(oxy))bis(ethan-1-amine) terminated PEG; 18-Unit PEG Diamine; O,O'-Bis(2-aminoethyl)octadeca(oxyethylene); Amino-PEG900-Amine; Jeffamine® EDR-148 (structural analog)
EINECS	Contact for details

Quality Control

Our O,O'-Bis(2-Aminoethyl)Octadecaethylene Glycol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, consistent molecular weight, and functional group integrity, meeting the stringent requirements for research and cGMP-grade applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C or as indicated on the label. Due to its hygroscopic nature, containers should be sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Assay (Purity)	≥ 95.0% (HPLC)
Molecular Weight (Mn)	850 - 950 g/mol (GPC)
Water Content	≤ 1.0% (KF Titration)
Amino Value	Contact for details
Heavy Metals	≤ 10 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.