Description

4-(Piperidin-4-Yl)Morpholin-3-One Hydrochloride is a high-purity pharmaceutical intermediate and building block of significant importance in modern organic synthesis. Its unique heterocyclic structure makes it a valuable precursor for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. This compound is essential for medicinal chemists and process development scientists in pharmaceutical, biotechnology, and fine chemical industries seeking to develop new therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for neurological and oncological targets.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its versatile piperidine-morpholinone scaffold.
• Process Chemistry & Scale-Up: Serves as a critical starting material for the pilot and commercial-scale production of advanced APIs.
• Bioconjugation & Probe Development: Utilized in the creation of chemical probes and labeled compounds for biochemical and pharmacological assays.
• Library Synthesis: A valuable component for generating diverse compound libraries in high-throughput screening (HTS) campaigns.
• Academic & Institutional Research: Employed in universities and research institutes for fundamental studies in heterocyclic chemistry and drug discovery.

Basic Information

Product Name	4-(Piperidin-4-Yl)Morpholin-3-One Hydrochloride
CAS No.	891790-19-5
Molecular Formula	C9H17ClN2O2
Molecular Weight	220.70 g/mol
Synonyms	4-(4-Piperidinyl)-3-morpholinone hydrochloride; 3-Morpholinone, 4-(4-piperidinyl)-, hydrochloride; 4-(Piperidin-4-yl)morpholin-3-one HCl; 4-(4-Piperidyl)morpholin-3-one hydrochloride; 891790-19-5; UNII-9J2F61C8QO; 9J2F61C8QO; AOB37717; SCHEMBL21806227; DTXSID60664688
EINECS	Contact for details

Quality Control

Our 4-(Piperidin-4-Yl)Morpholin-3-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm
Related Substances (HPLC)	Total impurities < 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.