Description

Sch-900776 is a high-purity, non-natural amino acid derivative and a key chiral building block in advanced pharmaceutical synthesis. This compound is critical for the research and development of novel therapeutic agents, particularly in the field of targeted oncology and enzyme inhibition. It is primarily utilized by pharmaceutical R&D laboratories, process chemistry teams, and fine chemical manufacturers engaged in the production of complex, high-value active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of investigational drug candidates, especially kinase inhibitors.
• Protease Inhibitor Research: Serves as a core structural component in the development of novel protease inhibitors for antiviral and anticancer applications.
• Peptidomimetic Chemistry: Used in the design and construction of peptidomimetics to enhance metabolic stability and bioavailability of peptide-based drugs.
• Asymmetric Synthesis: Employed as a sophisticated building block to introduce stereochemical complexity in multi-step synthetic routes.
• Chemical Biology & Proteomics: Utilized as a molecular tool or probe to study enzyme mechanisms and protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: A key starting material for CDMOs (Contract Development and Manufacturing Organizations) producing APIs under cGMP conditions.

Basic Information

Product Name	Sch-900776
CAS No.	891494-64-7
Molecular Formula	C₁₀H₁₉N₃O₃
Molecular Weight	229.28 g/mol
Synonyms	(2S)-2-Amino-3-[(2S)-2-azetidinyl]propanoic acid; L-Azetidine-2-carboxylic acid, 3-[(2S)-2-amino-2-carboxyethyl]-; (S)-3-((S)-Azetidin-2-yl)-2-aminopropanoic acid; SCH900776; SCH 900776; Azetidine amino acid derivative; Chiral azetidine building block
EINECS	Contact for details

Quality Control

Every batch of Sch-900776 (CAS 891494-64-7) is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure identity, purity, and enantiomeric excess meet the stringent requirements of pharmaceutical development. Certificates of Analysis (COA) with full traceability are provided for each lot, and we support compliance with cGMP, ICH Q7 guidelines, and REACH regulations for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the original container tightly sealed under an inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% e.e.
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.