Description

5-Piperazin-1-Yl-2-(Trifluoromethyl)-1,6-Naphthyridine CAS NO 890302-17-7 is a high-value, heterocyclic organic compound featuring a naphthyridine core substituted with a piperazine ring and a trifluoromethyl group. This specific molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily needed by R&D scientists and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and library synthesis due to its piperazine and trifluoromethyl motifs.
• Agrochemical Development: Employed in the research and development of new pesticides and herbicides, leveraging its heterocyclic structure.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying biological targets and pathways.
• Organic Synthesis Building Block: Acts as a versatile reagent for constructing complex nitrogen-containing heterocycles in academic and industrial laboratories.

Basic Information

Product Name	5-Piperazin-1-Yl-2-(Trifluoromethyl)-1,6-Naphthyridine
CAS No.	890302-17-7
Molecular Formula	C13H12F3N5
Molecular Weight	295.26 g/mol
Synonyms	2-(Trifluoromethyl)-5-(piperazin-1-yl)-1,6-naphthyridine; 5-(Piperazin-1-yl)-2-(trifluoromethyl)-1,6-naphthyridine; 1,6-Naphthyridine, 5-(1-piperazinyl)-2-(trifluoromethyl)-; 2-Trifluoromethyl-5-piperazin-1-yl-1,6-naphthyridine; 5-Piperazin-1-yl-2-trifluoromethyl-1,6-naphthyridine; 890302-17-7; UNII-9F6H9V2I4F
EINECS	Contact for details

Quality Control

Our 5-Piperazin-1-Yl-2-(Trifluoromethyl)-1,6-Naphthyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.