Description

2-[(4-Acetylpiperazin-1-Yl)Carbonyl]Benzoic Acid is a high-purity organic compound serving as a critical building block in advanced pharmaceutical synthesis. Its molecular structure, featuring both a benzoic acid and an acetylpiperazine moiety, makes it a versatile intermediate for developing novel active pharmaceutical ingredients (APIs). This compound is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the discovery and production of new therapeutic agents, particularly in areas requiring complex heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, especially for central nervous system (CNS) and oncology targets.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of complex APIs where its specific acetylpiperazine-carbonyl linkage is integral to the final molecule's activity.
• Chemical Research & Development: Serves as a valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials and commercial APIs.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in pharmaceutical laboratories.

Basic Information

Product Name	2-[(4-Acetylpiperazin-1-Yl)Carbonyl]Benzoic Acid
CAS No.	890092-07-6
Molecular Formula	C14H16N2O4
Molecular Weight	276.29 g/mol
Synonyms	2-[(4-Acetyl-1-piperazinyl)carbonyl]benzoic acid; 2-(4-Acetylpiperazine-1-carbonyl)benzoic acid; Benzoic acid, 2-[(4-acetyl-1-piperazinyl)carbonyl]-; 890092-07-6; 2-[(4-Acetylpiperazin-1-yl)carbonyl]benzoic acid; AKOS025310999; FT-0775785; 2-({4-[(E)-Acetyl]piperazin-1-yl}carbonyl)benzoic acid
EINECS	Contact for details

Quality Control

Our 2-[(4-Acetylpiperazin-1-Yl)Carbonyl]Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP applications. Certificates of Analysis (COA) detailing all test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.