Description

2-(4-Acetyl-Piperazin-1-Yl)-5-Chloroaniline is a high-purity, advanced pharmaceutical intermediate characterized by its unique piperazine-acetyl aniline structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of targeted therapeutic agents. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the creation of novel drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of novel herbicides and pesticides due to its chloroaniline moiety.
• Organic Synthesis: Serves as a versatile precursor for creating libraries of compounds in medicinal chemistry and high-throughput screening.
• API Development: Integral in the research and scale-up phases of new Active Pharmaceutical Ingredient (API) manufacturing.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	2-(4-Acetyl-Piperazin-1-Yl)-5-Chloroaniline
CAS No.	890091-78-8
Molecular Formula	C12H16ClN3O
Molecular Weight	253.73 g/mol
Synonyms	1-[4-(4-Amino-2-chlorophenyl)piperazin-1-yl]ethanone; 5-Chloro-2-(4-acetylpiperazin-1-yl)aniline; N-(4-Acetylpiperazin-1-yl)-5-chloro-2-aminobenzene; 2-Amino-4-chloro-N-(1-acetylpiperidin-4-yl)benzamide (isomer); 890091-78-8; AKOS BRN 1251; ZINC000003878756
EINECS	Contact for details

Quality Control

Our 2-(4-Acetyl-Piperazin-1-Yl)-5-Chloroaniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.