Description

C16 (2'(S)-Hydroxy) Ceramide (D18:1/16:0) is a specific, high-purity sphingolipid essential for advanced research and formulation in lipid biochemistry. This compound matters as a critical standard and active ingredient for studying and modulating skin barrier function, cellular signaling, and apoptosis. It is needed by researchers and product developers in the pharmaceutical, advanced dermatological, and high-end cosmetic industries seeking to innovate in areas of skin health and cellular biology. CAS No. 890041-50-6.

Application

• Biomedical Research Standard: Used as a certified reference material for quantitative analysis of ceramide species in biological samples via LC-MS or HPLC.
• Skin Barrier Studies: Incorporated into model lipid membranes to investigate stratum corneum structure, permeability, and repair mechanisms.
• Advanced Cosmetic Actives: Serves as a key bioactive component in premium anti-aging, moisturizing, and restorative skincare formulations.
• Cell Signaling Research: Applied in studies of sphingolipid-mediated pathways, including those involved in apoptosis, differentiation, and stress responses.
• Drug Delivery Systems: Explored as a component in lipid-based nanocarriers (e.g., liposomes, SLNs) for enhanced topical or transdermal delivery.
• Diagnostic Assay Development: Utilized in the development and calibration of clinical assays for measuring ceramide levels related to dermatological conditions.

Basic Information

Product Name	C16 (2'(S)-Hydroxy) Ceramide (D18:1/16:0)
CAS No.	890041-50-6
Molecular Formula	C34H65NO4
Molecular Weight	551.89 g/mol
Synonyms	N-[(2S,3R,4E)-2-Hydroxy-3-octadecenoyl]-D-erythro-sphingosine; (2S)-2-Hydroxy-N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]hexadecanamide; Ceramide (d18:1/16:0(2OH)); 2-Hydroxy-C16-Ceramide (d18:1/16:0); α-Hydroxy C16 Ceramide; N-(α-Hydroxypalmitoyl)-D-erythro-sphingosine; Phytosphingosine-based ceramide analog; Skin-identical ceramide
EINECS	Contact for details

Quality Control

Our C16 (2'(S)-Hydroxy) Ceramide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and MS, to ensure compliance with research-grade specifications. Comprehensive Certificates of Analysis (COA) detailing purity, related substances, and physical properties are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The material is hygroscopic; keep the container tightly sealed in a dry environment to minimize moisture uptake. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.