Description

2-(3-Oxo-Piperazine-1-Carbonyl)-Benzoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique piperazinone-benzoic acid hybrid structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic scaffolds. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for developing new drug candidates, including protease inhibitors and other targeted small molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting enzymatic pathways.
• Protease Inhibitor Development: Used in research and production of potential inhibitors for various proteases.
• Chemical Biology & Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• API Synthesis: Incorporated into the final steps or as a precursor in the manufacturing of complex Active Pharmaceutical Ingredients.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	2-(3-Oxo-Piperazine-1-Carbonyl)-Benzoic Acid
CAS No.	889958-03-6
Molecular Formula	C13H14N2O4
Molecular Weight	262.26 g/mol
Synonyms	2-[(3-Oxopiperazin-1-yl)carbonyl]benzoic acid; 1-(2-Carboxybenzoyl)-3-oxopiperazine; Benzoic acid, 2-[(3-oxo-1-piperazinyl)carbonyl]-; 2-(3-Oxopiperazine-1-carbonyl)benzoic acid; 2-(3-Oxopiperazine-1-carbonyl)benzoate; 889958-03-6; 2-(3-Oxo-1-piperazinylcarbonyl)benzoic acid
EINECS	Contact for details

Quality Control

Every batch of 2-(3-Oxo-Piperazine-1-Carbonyl)-Benzoic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.