Description

2-(3-Methyl-Piperazin-1-Yl)-Nicotinic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure. This compound is of significant commercial importance for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors, particularly those developing novel therapeutic agents. Its reliable quality and consistent supply are essential for ensuring the integrity of downstream drug development and production processes.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug molecules, particularly those targeting the central nervous system.
• API Synthesis: Serves as a crucial building block for constructing the core scaffold of various active pharmaceutical ingredients.
• Medicinal Chemistry Research: Used in research and development for creating new chemical entities and exploring structure-activity relationships.
• Bioconjugation: Potential use in the development of antibody-drug conjugates (ADCs) or other targeted therapies due to its functional groups.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method validation in pharmaceutical analysis.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	2-(3-Methyl-Piperazin-1-Yl)-Nicotinic Acid
CAS No.	889957-87-3
Molecular Formula	C11H15N3O2
Molecular Weight	221.26 g/mol
Synonyms	2-(3-Methylpiperazin-1-yl)nicotinic acid; Nicotinic acid, 2-(3-methyl-1-piperazinyl)-; 2-(3-Methyl-1-piperazinyl)nicotinic acid; 2-(3-Methylpiperazin-1-yl)pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 2-(3-methyl-1-piperazinyl)-; 889957-87-3
EINECS	Contact for details

Quality Control

Our 2-(3-Methyl-Piperazin-1-Yl)-Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical applications. Specifications typically align with in-house pharmacopeial standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.