Description

2-Carboxymethyl-5,5-Dimethyl-Morpholine-4-Carboxylic Acid tert-Butyl Ester is a high-value, protected morpholine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring a versatile intermediate with orthogonal protecting groups for the precise construction of complex molecules. It is primarily utilized in the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals where controlled functional group manipulation is paramount.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly in medicinal chemistry programs targeting nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents, including herbicides and fungicides with specific activity profiles.
• Peptidomimetics & Bioactive Molecule Construction: The morpholine and carboxylic acid ester functionalities make it valuable for creating peptide analogs and other bioactive scaffolds.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and metal complexation.
• Custom Chemical Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring protected amino acid-like structures.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and exploring new chemical spaces in discovery chemistry.

Basic Information

Product Name	2-Carboxymethyl-5,5-Dimethyl-Morpholine-4-Carboxylic Acid tert-Butyl Ester
CAS No.	889953-52-0
Molecular Formula	C13H23NO5
Molecular Weight	273.33 g/mol
Synonyms	tert-Butyl 2-(carboxymethyl)-5,5-dimethylmorpholine-4-carboxylate; 4-(tert-Butoxycarbonyl)-5,5-dimethylmorpholine-2-acetic Acid; 2-(Carboxymethyl)-5,5-dimethyl-4-morpholinecarboxylic Acid 1,1-Dimethylethyl Ester; Boc-DMOMA-OH; 5,5-Dimethylmorpholine-2,4-dicarboxylic Acid 4-tert-Butyl Ester 2-Acetic Acid; N-Boc-2-carboxymethyl-5,5-dimethylmorpholine
EINECS	Contact for details

Quality Control

Every batch of 2-Carboxymethyl-5,5-Dimethyl-Morpholine-4-Carboxylic Acid tert-Butyl Ester is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent batch-to-batch quality suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if opened, and desiccate if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.