Description

4-(4-Methylpiperazin-1-yl)pentanoic acid dihydrochloride monohydrate is a high-purity, functionalized piperazine derivative of significant importance in advanced organic synthesis. This compound serves as a versatile and critical building block for the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate a modified piperazine moiety into complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific piperazine-based structures.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in catalytic processes and metal complexation.
• Bioconjugation and Linker Chemistry: The carboxylic acid functionality allows for coupling reactions, useful in creating antibody-drug conjugates (ADCs) or diagnostic probes.
• Material Science Research: Employed in the synthesis of functional polymers and dendrimers with tailored chemical properties.
• Chemical Biology Tool Development: Used to create molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	4-(4-Methylpiperazin-1-yl)pentanoic acid dihydrochloride monohydrate
CAS No.	889939-93-9
Molecular Formula	C₁₀H₂₃Cl₂N₂O₃
Molecular Weight	290.21 g/mol
Synonyms	4-(4-Methyl-1-piperazinyl)pentanoic acid dihydrochloride hydrate; 4-(4-Methylpiperazin-1-yl)valeric acid hydrochloride hydrate; Pentanoic acid, 4-(4-methyl-1-piperazinyl)-, hydrochloride, hydrate (1:2:1); 4-(N-Methylpiperazino)pentanoic acid dihydrochloride monohydrate; 889939-93-9; 4-(4-Methylpiperazin-1-yl)pentanoic acid 2HCl·H₂O
EINECS	Contact for details

Quality Control

Our 4-(4-Methylpiperazin-1-yl)pentanoic acid dihydrochloride monohydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for water content, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	5.0% - 7.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.