Description

7(S),17(S)-Dihydroxy-8(E),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid is a specialized, highly unsaturated dihydroxy fatty acid derivative, representing a key intermediate and reference standard in lipidomics and bioactive lipid research. Its precise stereochemistry and conjugated polyene structure make it a critical compound for investigating the biosynthesis and physiological roles of specialized pro-resolving mediators (SPMs) and oxylipins. This high-purity material is essential for researchers and developers in pharmaceutical R&D, biotechnology, and advanced nutraceutical formulation, where understanding lipid signaling pathways is paramount.

Application

• Biochemical Research Standard: Serves as a certified reference material (CRM) for the quantification and identification of related oxylipin metabolites in biological samples via LC-MS/MS.
• Pharmaceutical Development: Utilized as a key intermediate in the synthesis and study of novel anti-inflammatory and pro-resolving lipid mediators targeting chronic inflammatory diseases.
• Cell Signaling Studies: Applied in in vitro and in vivo models to elucidate the mechanisms of action of dihydroxy fatty acids in immune modulation and resolution of inflammation.
• Enzymology: Acts as a substrate or product analog for studying the activity and specificity of lipoxygenase (LOX) and cytochrome P450 enzymes involved in polyunsaturated fatty acid metabolism.
• Nutraceutical Research: Investigated for its potential bioactivity as a component of advanced marine oil concentrates or as a marker for product efficacy and standardization.
• Diagnostic Kit Development: Used in the production of calibrators and controls for immunoassays or mass spectrometry-based diagnostic tests targeting inflammatory biomarkers.

Basic Information

Product Name	7(S),17(S)-Dihydroxy-8(E),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid
CAS No.	887752-13-8
Molecular Formula	C22H34O4
Molecular Weight	362.50 g/mol
Synonyms	7(S),17(S)-DiHDPA; (7S,17S)-dihydroxydocosa-8E,10Z,13Z,15E,19Z-pentaenoic acid; 7,17-DiHDPA n-3 DPA; 7(S),17(S)-DiHDPA; 7,17-Dihydroxydocosapentaenoic Acid; Resolvin D5 n-3 DPA isomer; RvD5n-3 DPA (stereoisomer); SPM precursor
EINECS	Contact for details

Quality Control

Every batch of our high-purity lipid standards is manufactured and analyzed under strict quality protocols. We guarantee identity, purity, and stability through a comprehensive suite of analytical techniques. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting results for assay, stereochemical purity, and related substances. Our quality system supports research requiring materials traceable to GMP/GLP standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store unopened vials at -20°C or below under an inert atmosphere (e.g., argon or nitrogen). Once opened, use immediately or aliquot under inert gas to minimize oxidation. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC/MS)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC, Area %)	≥ 95.0%
Purity (HPLC, UV)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% (7S,17S)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.