Description

1-Boc-4-(4-Acetyl-2-Amino-Phenyl)-4H-Pyrazine is a high-purity, advanced pharmaceutical intermediate featuring a protected amino group and a pyrazine core. This compound is critical for the synthesis of complex molecules, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Synthesis: Used in the development of new active ingredients for crop protection products.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and functional materials requiring complex heterocyclic structures.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting cutting-edge organic synthesis and chemical biology research.
• Process Chemistry Development: Used to develop and scale up efficient, cost-effective synthetic routes for commercial production.

Basic Information

Product Name	1-Boc-4-(4-Acetyl-2-Amino-Phenyl)-4H-Pyrazine
CAS No.	887595-40-6
Molecular Formula	C₁₇H₁₉N₃O₃
Molecular Weight	313.35 g/mol
Synonyms	tert-Butyl 4-(4-acetyl-2-aminophenyl)-4H-pyrazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(4-acetyl-2-aminophenyl)-4H-pyrazine; 4-(4-Acetyl-2-aminophenyl)-1-Boc-4H-pyrazine; 1-Boc-4-(4-acetyl-2-aminophenyl)pyrazine; N-Boc-4-(4-acetyl-2-aminophenyl)-4H-pyrazine; 4H-Pyrazine-1-carboxylic acid, 4-[4-acetyl-2-aminophenyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 1-Boc-4-(4-Acetyl-2-Amino-Phenyl)-4H-Pyrazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.