Description

1-[3-Amino-4-(4-Methyl-4H-Pyrazin-1-Yl)-Phenyl]-Ethanone is a high-purity, advanced pharmaceutical intermediate characterized by its distinct molecular structure containing both amino and pyrazinyl functional groups. This compound is critical for research and development in medicinal chemistry, serving as a key building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on developing new therapeutic agents, particularly in areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Synthesis: Used in the production of complex, high-value specialty chemicals and other advanced intermediates.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) settings for exploratory synthetic chemistry and methodological development.
• API Development: Integral to the development and scale-up processes for new Active Pharmaceutical Ingredients (APIs) requiring its specific heterocyclic core.

Basic Information

Product Name	1-[3-Amino-4-(4-Methyl-4H-Pyrazin-1-Yl)-Phenyl]-Ethanone
CAS No.	887595-34-8
Molecular Formula	C13H13N3O
Molecular Weight	227.26 g/mol
Synonyms	1-(3-Amino-4-(4-methyl-4H-pyrazin-1-yl)phenyl)ethanone; 1-[3-Amino-4-(4-methylpyrazin-1-ium-1-yl)phenyl]ethanone; Ethanone, 1-[3-amino-4-(4-methyl-4H-pyrazin-1-yl)phenyl]-; 3'-Amino-4'-(4-methyl-1-pyrazinio)acetophenone; CAS 887595-34-8
EINECS	Contact for details

Quality Control

Every batch of 1-[3-Amino-4-(4-Methyl-4H-Pyrazin-1-Yl)-Phenyl]-Ethanone is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to guarantee full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.