Description

4-(2-Bromo-Benzenesulfonyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its bromo-benzenesulfonyl and protected piperidine carboxylic acid ester functional groups. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents and specialty molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting neurological disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its modifiable sulfonyl and ester groups.
• API Synthesis: Serves as a precursor in multi-step synthetic routes for the production of complex, biologically active molecules.
• Chemical Library Development: Employed in combinatorial chemistry and high-throughput screening to create diverse compound libraries for biological testing.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and pesticides.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	4-(2-Bromo-Benzenesulfonyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	887591-20-0
Molecular Formula	C16H22BrNO4S
Molecular Weight	404.32 g/mol
Synonyms	1-Boc-4-[(2-bromophenyl)sulfonyl]piperidine; tert-Butyl 4-[(2-bromophenyl)sulfonyl]piperidine-1-carboxylate; 4-(2-Bromobenzenesulfonyl)piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-[(2-bromophenyl)sulfonyl]piperidine; N-Boc-4-(2-bromobenzenesulfonyl)piperidine; 4-(2-Bromo-phenylsulfonyl)-piperidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 4-(2-Bromo-Benzenesulfonyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive analytical data, including HPLC, NMR, and mass spectrometry results. Certificates of Analysis (COA) are available for every batch and provided upon request, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be stored away from direct light exposure. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.