Description

1-Boc-2-[(2-Fluoro-Phenylamino)-Methyl]-Piperidine is a high-purity, advanced pharmaceutical intermediate featuring a protected piperidine scaffold with a fluorinated aniline moiety. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules targeting central nervous system and other therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new drug candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, especially those requiring a fluorinated piperidine pharmacophore.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for discovering new therapeutic agents.
• Protease Inhibitor Development: Serves as a precursor in the creation of inhibitors for various enzymatic targets.
• Ligand Synthesis for Receptor Studies: Employed in the preparation of ligands for neurological and GPCR receptor binding assays.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) producing bespoke compounds for client pipelines.
• Academic Research: Utilized in university and institutional labs for exploratory organic synthesis and methodological development.

Basic Information

Product Name	1-Boc-2-[(2-Fluoro-Phenylamino)-Methyl]-Piperidine
CAS No.	887587-89-5
Molecular Formula	C18H27FN2O2
Molecular Weight	322.42 g/mol
Synonyms	1-Boc-2-[(2-Fluoroanilino)methyl]piperidine; tert-Butyl 2-[(2-fluorophenylamino)methyl]piperidine-1-carboxylate; 2-[(2-Fluorophenylamino)methyl]piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-2-[(2-fluoroanilino)methyl]piperidine; N-Boc-2-((2-fluoroanilino)methyl)piperidine; 887587-89-5; 1-Boc-2-(2-fluoroanilinomethyl)piperidine
EINECS	Contact for details

Quality Control

Our 1-Boc-2-[(2-Fluoro-Phenylamino)-Methyl]-Piperidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.