Description

1-Boc-2-[(4-Bromo-Benzylamino)-Methyl]-Piperidine is a high-purity, advanced pharmaceutical intermediate featuring a protected piperidine scaffold. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for creating potential drug candidates, particularly in areas requiring sophisticated nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Process Chemistry Development: Serves as a critical starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Protease Inhibitor Synthesis: The structural motif is valuable in constructing inhibitors for various protease enzymes.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Useful for developing molecular probes to study biological pathways and protein function.

Basic Information

Product Name	1-Boc-2-[(4-Bromo-Benzylamino)-Methyl]-Piperidine
CAS No.	887587-84-0
Molecular Formula	C18H27BrN2O2
Molecular Weight	383.33 g/mol
Synonyms	1-Boc-2-[(4-Bromobenzylamino)methyl]piperidine; tert-Butyl 2-[[(4-bromophenyl)methylamino]methyl]piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-2-[(4-bromobenzylamino)methyl]piperidine; N-[(1-Boc-piperidin-2-yl)methyl]-4-bromobenzylamine; Piperidine, 1-[(1,1-dimethylethoxy)carbonyl]-2-[[[(4-bromophenyl)methyl]amino]methyl]-; Boc-2-(4-Bromo-benzylaminomethyl)-piperidine
EINECS	Contact for details

Quality Control

Our 1-Boc-2-[(4-Bromo-Benzylamino)-Methyl]-Piperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with full traceability are provided and can be tailored to meet specific client requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere to prevent degradation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.