Description

1-Boc-3-[(3-Bromo-Phenylamino)-Methyl]-Piperidine is a high-purity, advanced pharmaceutical intermediate featuring a piperidine scaffold with protected amine and brominated aniline functionalities. This compound matters for its critical role as a versatile building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry and drug discovery pipelines. Pharmaceutical R&D teams and fine chemical manufacturers need this intermediate to develop potential therapeutic agents targeting central nervous system (CNS) disorders and other disease areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold in the multi-step synthesis of potential APIs.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic & Industrial R&D: Employed in research laboratories for developing new synthetic methodologies and novel heterocyclic compounds.

Basic Information

Product Name	1-Boc-3-[(3-Bromo-Phenylamino)-Methyl]-Piperidine
CAS No.	887587-00-0
Molecular Formula	C18H27BrN2O2
Molecular Weight	383.33 g/mol
Synonyms	tert-Butyl 3-[[(3-bromophenyl)amino]methyl]piperidine-1-carboxylate; 1-Boc-3-[(3-Bromoanilino)methyl]piperidine; 1-(tert-Butoxycarbonyl)-3-[(3-bromophenylamino)methyl]piperidine; 3-[(3-Bromo-phenylamino)-methyl]-piperidine-1-carboxylic acid tert-butyl ester; N-(3-Bromophenyl)-N-(1-Boc-piperidin-3-ylmethyl)amine; 1-Boc-3-(3-bromoanilinomethyl)piperidine; 887587-00-0
EINECS	Contact for details

Quality Control

Our 1-Boc-3-[(3-Bromo-Phenylamino)-Methyl]-Piperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere or inert gas to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.