Description

1-Boc-3-(2-Bromo-Benzylamino)-Piperidine is a high-purity, advanced pharmaceutical intermediate featuring a protected piperidine scaffold with a bromo-benzylamino substituent. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets and kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its versatile, protected amine functionality.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes for active pharmaceutical ingredients (APIs).
• Chemical Biology Probes: Employed in the development of tool compounds and molecular probes for biological target validation.
• Custom Synthesis: A foundational substrate for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	1-Boc-3-(2-Bromo-Benzylamino)-Piperidine
CAS No.	887584-29-4
Molecular Formula	C17H25BrN2O2
Molecular Weight	369.30 g/mol
Synonyms	1-Boc-3-[(2-Bromophenyl)methylamino]piperidine; tert-Butyl 3-[(2-bromobenzyl)amino]piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-3-[(2-bromobenzyl)amino]piperidine; 3-[(2-Bromobenzyl)amino]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; Piperidine, 3-[(2-bromophenyl)methyl]amino]-1-(1,1-dimethylethoxy)carbonyl]-; 1-Boc-3-(2-Bromobenzylamino)piperidine; N-Boc-3-(2-bromobenzylamino)piperidine
EINECS	Contact for details

Quality Control

Our 1-Boc-3-(2-Bromo-Benzylamino)-Piperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.