Description

1-Boc-3-(4-Bromo-Phenylamino)-Piperidine is a high-purity, advanced pharmaceutical intermediate featuring a protected piperidine scaffold with a brominated aniline moiety. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new drug candidates, particularly in areas requiring complex amine functionalization.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to explore new chemical entities.
• Protecting Group Chemistry: The tert-butoxycarbonyl (Boc) group allows for selective deprotection, making it valuable for multi-step synthetic sequences.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands or organocatalysts used in asymmetric synthesis.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the custom production of complex molecules for clients.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	1-Boc-3-(4-Bromo-Phenylamino)-Piperidine
CAS No.	887584-22-7
Molecular Formula	C16H23BrN2O2
Molecular Weight	355.27 g/mol
Synonyms	1-Boc-3-(4-bromoanilino)piperidine; tert-Butyl 3-[(4-bromophenyl)amino]piperidine-1-carboxylate; 3-[(4-Bromophenyl)amino]-1-(tert-butoxycarbonyl)piperidine; 1-(tert-Butoxycarbonyl)-3-[(4-bromophenyl)amino]piperidine; Piperidine, 3-[(4-bromophenyl)amino]-1-[(1,1-dimethylethoxy)carbonyl]-; 887584-22-7; 1-Boc-3-(4-Br-Ph-NH)-piperidine
EINECS	Contact for details

Quality Control

Our 1-Boc-3-(4-Bromo-Phenylamino)-Piperidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.