Description

2-(Bromomethyl)-4-n-tert-Butoxycarbony-Piperazine is a specialized piperazine derivative, a crucial building block in modern organic synthesis. Its value lies in its dual functionality, featuring a reactive bromomethyl group and a tert-butoxycarbonyl (Boc) protected amine, enabling precise and sequential modifications. This compound is essential for researchers and manufacturers in the pharmaceutical industry, particularly for constructing complex molecules and active pharmaceutical ingredients (APIs) through targeted alkylation and amination reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in kinase inhibitors and central nervous system (CNS) agents.
• Peptidomimetic Chemistry: Used to introduce piperazine scaffolds into peptide backbones to enhance metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a versatile building block for creating chelating ligands and organocatalysts.
• Custom Chemical Synthesis: Employed in contract research and manufacturing (CRO/CMO) for bespoke molecular construction and library synthesis.
• Agrochemical Research: Utilized in the development of new crop protection agents with specific biological activity.
• Material Science: Acts as a monomer or cross-linking agent in the development of functional polymers and resins.

Basic Information

Product Name	2-(Bromomethyl)-4-n-tert-Butoxycarbony-Piperazine
CAS No.	887581-70-6
Molecular Formula	C11H21BrN2O2
Molecular Weight	293.20 g/mol
Synonyms	1-Boc-4-(bromomethyl)piperazine; tert-Butyl 4-(bromomethyl)piperazine-1-carboxylate; 4-(Bromomethyl)-1-N-Boc-piperazine; 1-(tert-Butoxycarbonyl)-4-(bromomethyl)piperazine; 4-(Bromomethyl)piperazine-1-carboxylic acid tert-butyl ester; N-Boc-4-(bromomethyl)piperazine; Piperazine, 4-(bromomethyl)-1-[(1,1-dimethylethoxy)carbonyl]-
EINECS	Contact for details

Quality Control

Our 2-(Bromomethyl)-4-n-tert-Butoxycarbony-Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.