Description

4-(2-Bromomethyl)-1-Piperazinecarboxylic Acid, 1,1-Dimethylethyl Ester is a versatile and high-purity Boc-protected piperazine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the reactive bromomethyl group, which enables efficient functionalization and chain extension, making it indispensable for constructing complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, receptor antagonists, and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides, where the piperazine scaffold contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Peptidomimetics & Bio-conjugation: The reactive bromomethyl handle is utilized for alkylation reactions in the design of peptidomimetic compounds and for bio-conjugation strategies.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying enzyme function and protein-protein interactions.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialized polymers and functional materials.

Basic Information

Product Name	4-(2-Bromomethyl)-1-Piperazinecarboxylic Acid, 1,1-Dimethylethyl Ester
CAS No.	887579-23-9
Molecular Formula	C11H21BrN2O2
Molecular Weight	293.20 g/mol
Synonyms	1-Boc-4-(bromomethyl)piperazine; tert-Butyl 4-(bromomethyl)piperazine-1-carboxylate; 4-(Bromomethyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-4-(bromomethyl)piperazine; N-Boc-4-(bromomethyl)piperazine; Piperazine, 4-(bromomethyl)-, 1-(1,1-dimethylethyl) 1-carboxylate; Boc-4-(bromomethyl)piperazine
EINECS	Contact for details

Quality Control

Our 4-(2-Bromomethyl)-1-Piperazinecarboxylic Acid, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.