Description

2-(4-Hydroxy-Piperidin-1-Yl)-Benzamidine is a high-purity chemical building block featuring a benzamidine core functionalized with a hydroxy-piperidine moiety. This compound is valued for its role as a versatile synthetic intermediate in advanced pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of protease inhibitors and other biologically active molecules targeting various disease pathways.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its modifiable functional groups.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new crop protection agents and pesticides.
• Chemical Biology Probes: Employed in the development of tool compounds and probes for studying enzyme function and biological mechanisms.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs engaged in custom chemical synthesis for clients.

Basic Information

Product Name	2-(4-Hydroxy-Piperidin-1-Yl)-Benzamidine
CAS No.	887577-43-7
Molecular Formula	C12H17N3O
Molecular Weight	219.28 g/mol
Synonyms	1-(4-Hydroxypiperidin-1-yl)benzenecarboximidamide; Benzamidine, 2-(4-hydroxy-1-piperidinyl)-; 2-(4-Hydroxypiperidin-1-yl)benzamidine; 2-(4-Hydroxy-1-piperidinyl)benzamidine; 887577-43-7; 2-(4-Hydroxy-piperidin-1-yl)-benzamidine
EINECS	Contact for details

Quality Control

Our 2-(4-Hydroxy-Piperidin-1-Yl)-Benzamidine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.