Description

4-Aminomethyl-2-(4-Methyl-Piperazin-1-Yl)-Phenol is a versatile and high-value pharmaceutical intermediate featuring a unique phenolic and piperazine-based structure. This compound matters for its critical role in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. Pharmaceutical research and development organizations, as well as fine chemical manufacturers, need this high-purity building block to develop new drug candidates and scale up production processes efficiently.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and receptor-targeted therapies.
• Chemical Synthesis Reagent: Used in organic synthesis for introducing the aminomethyl-phenol and N-methylpiperazine moieties into more complex molecules.
• Research & Development: Serves as a crucial starting material or intermediate in medicinal chemistry and drug discovery programs for hit-to-lead optimization.
• Ligand and Chelator Precursor: Its structure makes it a potential precursor for developing ligands in catalysis or chelating agents in various chemical processes.

Basic Information

Product Name	4-Aminomethyl-2-(4-Methyl-Piperazin-1-Yl)-Phenol
CAS No.	887577-33-5
Molecular Formula	C12H19N3O
Molecular Weight	221.30 g/mol
Synonyms	4-(Aminomethyl)-2-(4-methylpiperazin-1-yl)phenol; 2-(4-Methyl-1-piperazinyl)-4-(aminomethyl)phenol; 1-[5-(Aminomethyl)-2-hydroxyphenyl]-4-methylpiperazine; Phenol, 4-(aminomethyl)-2-(4-methyl-1-piperazinyl)-; 887577-33-5
EINECS	Contact for details

Quality Control

Our 4-Aminomethyl-2-(4-Methyl-Piperazin-1-Yl)-Phenol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.