Description

5-Oxo-1-(2-Piperazin-1-Yl-Ethyl)-Pyrrolidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate featuring a unique pyrrolidone-piperazine hybrid structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and neuropharmacological agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process chemistry for producing innovative therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules targeting neurological and psychiatric disorders.
• Drug Discovery & Medicinal Chemistry: Used in research for creating and screening new chemical entities (NCEs) with potential therapeutic activity.
• Process Development & Scale-up: Serves as a critical starting material or intermediate for optimizing and scaling API manufacturing processes under GMP conditions.
• Bioconjugation & Probe Development: Its functional groups make it suitable for creating biochemical probes and conjugates for diagnostic or research purposes.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.

Basic Information

Product Name	5-Oxo-1-(2-Piperazin-1-Yl-Ethyl)-Pyrrolidine-3-Carboxylic Acid
CAS No.	887405-33-6
Molecular Formula	C11H19N3O3
Molecular Weight	241.29 g/mol
Synonyms	1-(2-(Piperazin-1-yl)ethyl)-5-oxopyrrolidine-3-carboxylic acid; 5-Oxo-1-[2-(1-piperazinyl)ethyl]-3-pyrrolidinecarboxylic acid; 5-Oxo-1-(2-piperazin-1-ylethyl)pyrrolidine-3-carboxylic acid; Pyrrolidine-3-carboxylic acid, 5-oxo-1-[2-(1-piperazinyl)ethyl]-; CAS 887405-33-6
EINECS	Contact for details

Quality Control

Our 5-Oxo-1-(2-Piperazin-1-Yl-Ethyl)-Pyrrolidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting its use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.