Description

Ethyl 2-Piperazine-4-(2,5-Difluoro)Phenyl Thiazole-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in modern organic synthesis, particularly for the development of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the discovery and scale-up of new drug candidates, especially within therapeutic areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex heterocyclic molecules and exploring new chemical spaces.
• Agrochemical Development: Serves as a precursor in the research phase for creating new active ingredients with specific biological activity.
• Material Science: Potential application in the synthesis of specialty chemicals and functional materials requiring specific fluorine-containing motifs.

Basic Information

Product Name	Ethyl 2-Piperazine-4-(2,5-Difluoro)Phenyl Thiazole-5-Carboxylate
CAS No.	887267-68-7
Molecular Formula	C16H17F2N3O2S
Molecular Weight	353.39 g/mol
Synonyms	Ethyl 2-(4-(2,5-difluorophenyl)piperazin-1-yl)thiazole-5-carboxylate; 2-(4-(2,5-Difluorophenyl)-1-piperazinyl)-5-thiazolecarboxylic Acid Ethyl Ester; 887267-68-7; Ethyl 2-[4-(2,5-difluorophenyl)piperazin-1-yl]-1,3-thiazole-5-carboxylate; 5-Thiazolecarboxylic acid, 2-[4-(2,5-difluorophenyl)-1-piperazinyl]-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Piperazine-4-(2,5-Difluoro)Phenyl Thiazole-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet specific client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; therefore, containers should be kept sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.