Description

2-Amino-5-Iodopyrazine is a versatile halogenated pyrazine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of both an amino group and an iodine atom on the pyrazine ring, enabling a wide range of cross-coupling and functionalization reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require specific heterocyclic scaffolds.
• Material Science: Building block for creating organic electronic materials, ligands for catalysts, and specialty polymers.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for Suzuki, Sonogashira, and Buchwald-Hartwig amination reactions.
• Chemical Biology: Useful for labeling and modifying biomolecules in probe development and bioconjugation strategies.
• Academic & R&D: Fundamental reagent for exploring new synthetic methodologies and constructing complex molecular libraries.

Basic Information

Product Name	2-Amino-5-Iodopyrazine
CAS No.	886860-50-0
Molecular Formula	C4H4IN3
Molecular Weight	221.00 g/mol
Synonyms	5-Iodo-2-pyrazinamine; 5-Iodopyrazin-2-amine; 2-Pyrazinamine, 5-iodo-; 2-Amino-5-iodopyrazine; 886860-50-0; 5-Iodo-2-aminopyrazine; 2-Amino-5-iodo-1,4-diazine
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Iodopyrazine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your internal quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.