Description

4-(3-Hydroxyphenyl)-1,4-Diazepane, N1-Boc Protected 95%tert-Butyl 4-(3-Hydroxyphenyl)Perhydro-1,4-Diazepine-1-Carboxylate is a high-purity, protected intermediate essential for advanced organic synthesis. This compound matters because it provides a critical, functionalized building block for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting the central nervous system (CNS) or requiring a functionalized diazepane scaffold.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new therapeutic agents.
• Peptidomimetic Synthesis: Serves as a constrained scaffold or a building block for creating peptide analogs with enhanced stability and bioavailability.
• Agrochemical Development: Employed in the research and synthesis of novel herbicides, fungicides, or insecticides that utilize heterocyclic chemistry.
• Ligand and Catalyst Development: The phenolic hydroxyl and protected amine groups make it a useful starting material for creating specialized ligands in coordination chemistry and catalysis.
• Custom Synthesis and Contract Manufacturing: A vital component for custom synthesis houses producing bespoke chemicals for client-specific research programs.

Basic Information

Product Name	4-(3-Hydroxyphenyl)-1,4-Diazepane, N1-Boc Protected 95%tert-Butyl 4-(3-Hydroxyphenyl)Perhydro-1,4-Diazepine-1-Carboxylate
CAS No.	886851-68-9
Molecular Formula	C₁₇H₂₆N₂O₃
Molecular Weight	306.40 g/mol
Synonyms	tert-Butyl 4-(3-hydroxyphenyl)-1,4-diazepane-1-carboxylate; 1-Boc-4-(3-hydroxyphenyl)homopiperazine; 1-(tert-Butoxycarbonyl)-4-(3-hydroxyphenyl)homopiperazine; 4-(3-Hydroxyphenyl)homopiperazine-1-carboxylic acid tert-butyl ester; N-Boc-4-(3-hydroxyphenyl)-1,4-diazepane; 1,4-Diazepane-1-carboxylic acid, 4-(3-hydroxyphenyl)-, 1,1-dimethylethyl ester; Perhydro-1,4-diazepine-1-carboxylic acid, 4-(3-hydroxyphenyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 4-(3-Hydroxyphenyl)-1,4-Diazepane, N1-Boc Protected is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect the product from moisture. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.