Description

tert-Butyl 2,3-Diphenylpiperazine-1-Carboxylate is a high-purity, protected piperazine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile chiral intermediate, enabling the construction of complex molecules with precise stereochemistry. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers developing active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, especially for neurological and psychiatric applications.
• Asymmetric Synthesis: Utilized in the construction of complex, stereochemically defined molecular architectures due to its diphenyl-substituted piperazine core.
• Medicinal Chemistry Research: Serves as a scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry & Scale-Up: Employed in the development and optimization of synthetic routes for pilot and commercial-scale API manufacturing.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis organizations producing specialized fine chemicals for clients.
• Academic & Institutional Research: Used in university and institutional labs for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	tert-Butyl 2,3-Diphenylpiperazine-1-Carboxylate
CAS No.	886780-65-0
Molecular Formula	C21H26N2O2
Molecular Weight	338.45 g/mol
Synonyms	1-Boc-2,3-diphenylpiperazine; 2,3-Diphenylpiperazine-1-carboxylic acid tert-butyl ester; tert-Butyl 2,3-diphenyl-1-piperazinecarboxylate; 1-(tert-Butoxycarbonyl)-2,3-diphenylpiperazine; Boc-2,3-diphenylpiperazine; 886780-65-0; 2,3-Diphenyl-1-Boc-piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 2,3-Diphenylpiperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.