Description

2,3-Dimethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-value, Boc-protected piperazine derivative that serves as a critical chiral building block in advanced organic synthesis. Its primary value lies in providing a protected secondary amine functionality, enabling precise control over molecular architecture in complex multi-step reactions. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, especially for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used as a building block for creating advanced, high-efficacy pesticides and herbicides with specific stereochemical requirements.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: Integral for constructing constrained peptide analogs and peptidomimetic scaffolds in medicinal chemistry.
• Custom Chemical Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring protected diamine units.

Basic Information

Product Name	2,3-Dimethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	886780-49-0
Molecular Formula	C11H22N2O2
Molecular Weight	214.31 g/mol
Synonyms	1-Boc-2,3-dimethylpiperazine; tert-Butyl 2,3-dimethylpiperazine-1-carboxylate; 2,3-Dimethyl-1-N-Boc-piperazine; 1-(tert-Butoxycarbonyl)-2,3-dimethylpiperazine; 2,3-Dimethylpiperazine-1-carboxylic acid tert-butyl ester; Boc-2,3-dimethylpiperazine; (2,3-Dimethylpiperazin-1-yl)(tert-butoxy)methanone
EINECS	Contact for details

Quality Control

Our 2,3-Dimethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) for each lot. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% (for chiral grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.