Description

2-Phenethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, protected piperazine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily required by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides requiring specific piperazine-based scaffolds.
• Peptide Mimetics & Conjugates: Serves as a protected amine component for creating peptide-like structures and bioconjugates.
• Ligand Synthesis for Catalysis: Employed in the preparation of specialized ligands for asymmetric catalysis and metal complexation.
• Chemical Biology Probes: Utilized to create molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Item	Details
Product Name	2-Phenethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	886779-53-9
Molecular Formula	C17H26N2O2
Molecular Weight	290.40 g/mol
Synonyms	tert-Butyl 2-phenethylpiperazine-1-carboxylate; 1-Boc-2-phenethylpiperazine; 2-Phenethyl-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; N-Boc-2-phenethylpiperazine; 1-(tert-Butoxycarbonyl)-2-phenethylpiperazine; Boc-2-phenethylpiperazine; 886779-53-9
EINECS	Contact for details

Quality Control

Our 2-Phenethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment. We support development and commercial projects requiring compliance with ICH guidelines and can supply material suitable for cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.