Description

3-(4-Nitro-Benzyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, protected piperazine derivative of significant importance in modern organic synthesis. This compound serves as a critical building block for the development of novel pharmaceutical intermediates and active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the piperazine scaffold's prevalence in bioactive molecules.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides where the nitro-benzyl and piperazine functionalities impart specific biological activity.
• Chemical Biology & Proteomics: Employed as a versatile linker or spacer molecule in the design of chemical probes, affinity tags, and bioconjugation reagents.
• Material Science: Acts as a monomer or functionalizing agent in the synthesis of specialized polymers and advanced organic materials.
• Academic & Contract Research: Essential for medicinal chemistry programs in academic laboratories and contract research organizations (CROs) for structure-activity relationship (SAR) studies.
• Custom Synthesis: Serves as a starting material for the custom synthesis of more complex, proprietary compounds for client-specific applications.

Basic Information

Product Name	3-(4-Nitro-Benzyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	886774-93-2
Molecular Formula	C16H23N3O4
Molecular Weight	321.37 g/mol
Synonyms	1-Boc-3-(4-Nitrobenzyl)piperazine; tert-Butyl 3-(4-Nitrobenzyl)piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-3-(4-nitrobenzyl)piperazine; 3-(4-Nitrobenzyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; 1-Boc-3-(4-nitrobenzyl)piperazine; N-Boc-3-(4-Nitrobenzyl)piperazine; Piperazine-1-carboxylic acid tert-butyl ester, 3-(4-nitrobenzyl)- derivative
EINECS	Contact for details

Quality Control

Our 3-(4-Nitro-Benzyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our commitment to quality assurance and supply chain reliability makes us a trusted partner for critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.