Description

2-(4-Chloro-Benzyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, protected piperazine derivative that serves as a critical building block in modern pharmaceutical synthesis. This compound is valued for its role as a versatile intermediate, enabling the efficient construction of complex molecules with potential biological activity. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs), particularly in areas requiring sophisticated nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs), leveraging its protected amine functionality for selective reactions.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes within drug discovery pipelines.
• Custom Synthesis Building Block: Serves as a specialized starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds.
• Chemical Biology Probes: Can be utilized in the synthesis of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	2-(4-Chloro-Benzyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	886772-68-5
Molecular Formula	C17H25ClN2O2
Molecular Weight	324.85 g/mol
Synonyms	tert-Butyl 2-[(4-chlorophenyl)methyl]piperazine-1-carboxylate; 1-Boc-2-(4-Chlorobenzyl)piperazine; 2-(4-Chlorobenzyl)-1-Boc-piperazine; 1-(tert-Butoxycarbonyl)-2-(4-chlorobenzyl)piperazine; N-Boc-2-(4-Chlorobenzyl)piperazine; 2-(p-Chlorobenzyl)-1-Boc-piperazine; 886772-68-5; 2-(4-Chlorobenzyl)piperazine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 2-(4-Chloro-Benzyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards expected for pharmaceutical intermediates in global supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.