Description

3-Furan-2-Yl-Piperazine-1-Carboxylic Acid tert-Butyl Ester CAS NO 886771-26-2 is a high-purity, advanced pharmaceutical intermediate belonging to the piperazine class of heterocyclic compounds. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily required by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and fine chemical producers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used extensively in hit-to-lead optimization and structure-activity relationship (SAR) studies to develop new pharmacophores.
• API Development: A key scaffold for constructing novel Active Pharmaceutical Ingredients (APIs) with potential applications in antipsychotic, antidepressant, or anticancer therapies.
• Contract Manufacturing: Supplied to CROs and CDMOs for custom synthesis and scale-up projects under GMP or non-GMP conditions.
• Chemical Library Synthesis: Employed in the creation of diverse compound libraries for high-throughput screening (HTS) in drug discovery programs.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Item	Details
Product Name	3-Furan-2-Yl-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	886771-26-2
Molecular Formula	C13H20N2O3
Molecular Weight	252.31 g/mol
Synonyms	tert-Butyl 3-(furan-2-yl)piperazine-1-carboxylate; 1-Boc-3-(2-furyl)piperazine; 3-(2-Furyl)-1-piperazinecarboxylic Acid 1,1-Dimethylethyl Ester; 1-(tert-Butoxycarbonyl)-3-(2-furyl)piperazine; 3-(Furan-2-yl)piperazine-1-carboxylic acid tert-butyl ester; 3-(2-Furanyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; Boc-3-(2-furyl)piperazine
EINECS	Contact for details

Quality Control

Our 3-Furan-2-Yl-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications from research to development scale, with the capability to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.