Description

3-(3,4,5-Trimethoxy-Phenyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound serves as a critical building block in the synthesis of complex molecules, particularly for medicinal chemistry applications. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting the central nervous system.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Custom Synthesis: Serves as a specialized starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening in drug discovery.
• Chemical Reference Standard: Utilized as an analytical standard for quality control and method development in API manufacturing.

Basic Information

Item	Details
Product Name	3-(3,4,5-Trimethoxy-Phenyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	886770-31-6
Molecular Formula	C18H28N2O5
Molecular Weight	352.43 g/mol
Synonyms	tert-Butyl 3-(3,4,5-trimethoxyphenyl)piperazine-1-carboxylate; 1-Boc-3-(3,4,5-trimethoxyphenyl)piperazine; 3-(3,4,5-Trimethoxyphenyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; 1-N-Boc-3-(3,4,5-trimethoxyphenyl)piperazine; 886770-31-6; 3-(3,4,5-Trimethoxyphenyl)piperazine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our production of 3-(3,4,5-Trimethoxy-Phenyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.