Description

tert-Butyl 2-(2H-1,3-Benzodioxol-5-yl)piperazine-1-carboxylate is a high-purity, protected piperazine derivative of significant interest in advanced organic synthesis. This compound serves as a crucial pharmaceutical intermediate and building block for the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and chemical manufacturers engaged in the synthesis of complex molecules for medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates, particularly those targeting the central nervous system.
• Medicinal Chemistry Research: Used as a versatile building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• API Development: Integral to the research and process development stages for new active pharmaceutical ingredients, leveraging its protected amine functionality.
• Custom Synthesis: Serves as a starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized fine chemicals.
• Chemical Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in pharmaceutical labs.

Basic Information

Product Name	tert-Butyl 2-(2H-1,3-Benzodioxol-5-yl)piperazine-1-carboxylate
CAS No.	886770-00-9
Molecular Formula	C16H22N2O4
Molecular Weight	306.36 g/mol
Synonyms	1-Boc-2-(1,3-benzodioxol-5-yl)piperazine; 2-(1,3-Benzodioxol-5-yl)-1-(tert-butoxycarbonyl)piperazine; tert-Butyl 2-(1,3-benzodioxol-5-yl)piperazine-1-carboxylate; 1,3-Benzodioxol-5-yl-piperazine-1-carboxylic acid tert-butyl ester; 2-(Benzo[d][1,3]dioxol-5-yl)-1-(tert-butoxycarbonyl)piperazine; BOC-Piperazine-Benzodioxole Derivative; 886770-00-9
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-(2H-1,3-Benzodioxol-5-yl)piperazine-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are available for every lot. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.